Dethiobiotin synthetase
WebWith a 2024 population of 490,270, it is the largest city in Georgia and the 39th largest city in the United States. Atlanta is currently declining at a rate of -0.63% annually and its … WebSep 5, 1995 · Mechanism of an ATP-Dependent Carboxylase, Dethiobiotin Synthetase, Based on Crystallographic Studies of Complexes with Substrates and a Reaction Intermediate. Biochemistry 1995, 34 (35) , 10985-10995.
Dethiobiotin synthetase
Did you know?
WebThe levels of dethiobiotin synthetase in Escherichia co2i have been increased 6-fold over the wild type when pre- pared from a X-lysogen carrying the bioD gene under phage control. The purification procedure employed gave a nearly … WebDethiobiotin synthetase from Mycobacterium tuberculosis (MtDTBS) is a promising antituberculosis drug target. Small-molecule inhibitors that target MtDTBS provide a route towards new therapeutics for the treatment of antibiotic-resistant tuberculosis. Adenosine diphosphate (ADP) is an inhibitor of MtDTBS; however, structural studies into its ...
Webdethiobiotin synthetase Synonyms: Evidence for Translation: Charge (pH 7)-7.44 Kyte-Doolittle Hydrophobicity Value: 0.323 Molecular Weight (kDa) 23.6 Isoelectric Point (pI) 5.02 Subcellular localization. Individual Mappings: Localization Confidence PMID; Cytoplasmic ... WebAug 31, 1998 · The crystal structures of two complexes of dethiobiotin synthetase, enzyme-diaminopelargonic acid-MgADP-AlF3 and enzyme-dethiobiotin-MgADP-Pi, respectively, have been determined to 1.8 A …
WebApr 17, 2024 · The ureido ring of dethiobiotin is formed by the enzyme dethiobiotin synthase (DTBS). The final step involves the insertion of sulfur and is catalyzed by the enzyme biotin synthase (BS). WebMar 31, 1998 · The ATP-dependent enzyme dethiobiotin synthetase from Escherichia coli catalyses the formation of dethiobiotin from CO2 and 7, 8-diaminopelargonic acid. The reaction is initiated by the formation of a carbamate and proceeds through a phosphorylated intermediate, a mixed carbamic phosphoric anhydride ... Macromolecules
WebGSE12663: virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages: GSE42863: Flagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii
WebJan 6, 2004 · The structure reveals a nearly symmetric 222 tetramer, in which each bifunctional monomer contains a dethiobiotin synthetase-like amidoligase N-terminal domain and a Type 1 glutamine amidotransferase C-terminal domain. For each amidoligase active site, essential ATP- and UTP-binding surfaces are contributed by three … how large does a ponytail palm getWebDethiobiotin synthetase. Dethiobiotin synthetase. Dethiobiotin synthetase Methods Enzymol. 1979;62:348-52. doi: 10.1016/0076-6879(79)62241-3. Authors M A Eisenberg, … how large does a roblox group icon have to beWebApr 7, 2024 · Atlanta, city, capital (1868) of Georgia, U.S., and seat (1853) of Fulton county (but also partly in DeKalb county). It lies in the foothills of the Blue Ridge Mountains in … how large do lilac bushes getWebMar 28, 1995 · One of these enzymes, ATP-dependent dethiobiotin synthetase, catalyzes the carboxylation of 7,8-diaminopelargonic acid leading to the formation of the ureido ring of biotin. The enzyme belongs to the class of ATP-dependent carboxylases and we present here the first crystal structure determined for this class of enzyme. how large does a septic drainfield need to behow large do pot belly pigs getWebNov 1, 2000 · Sequence analysis of this fragment revealed that it is closely related to a family of ATP-dependent enzymes that also includes dethiobiotin synthetase and the synthetase domains of two amidotransferases involved in cobalamin biosynthesis, cobyrinic acid a,c-diamide synthase (CobB) and cobyric acid synthase (CobQ). how large do miniature roses growWebSep 5, 1995 · Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF 3 -diaminopelargonic acid and enzyme-MgADP-dethiobiotin … how large do savannah cats get