Web9 apr. 2024 · Analysis of selection signatures was performed within a population using pooled heterozygosity (Hp) and integrated haplotype homozygosity (iHS). Among populations, it was performed using population differentiation (F ST) ... (p-value of 9.9 × 10 −3), corresponding to the top 0.5% iHS scores (Figure 7d, Table S4). Web28 mei 2024 · The ability of detecting adaptive (positive) selection in the genome has opened the possibility of understanding the genetic bases of population-specific adaptations genome-wide. Here we present the analysis of recent selective sweeps specifically in the X chromosome in different human populations from the third phase of the 1000 Genomes …
Genome-Wide Scan Identifies Selection Signatures in Chinese …
Web14 okt. 2024 · Three different methods were used to search for signals of selection: Tajima’s D (TD), the integrated haplotype score (iHS), and runs of homozygosity (ROH). The samples were composed of males ( n = 62) and females ( n = 130) that were initially chosen considering well-defined phenotypes for gait: picada ( n = 86) and batida ( n = 106). Web30 mei 2024 · In total, we obtained 478,903 SNPs and 24,820 no-overlap regions for iHS (integrated haplotype score) estimations. Under the threshold of the top 1%, 239 regions were finally identified as candidate selected regions and 162 candidate genes were found based on the UMD3.1 genome assembly. days inn johnson creek wi
A Map of Recent Positive Selection in the Human Genome
Web23 mrt. 2024 · The iHS score for each SNP was transformed into two-sided p-value as: piHS = − log 10 [1–2 Φ ( iHS )− 0.5 ], where Φ ( iHS) is the cumulative Gaussian distribution function of iHS [ 24 ]. For the Rsb and XP-EHH tests, haplotypes were reconstructed from the genotyped SNPs using the fastPHASE 1.4 software [ 25 ]. http://www.reeis.usda.gov/web/crisprojectpages/0209190-haplotype-analysis-from-bovine-genotype-data.html Web1 apr. 2024 · We have implemented a large number of summary statistics informative for the action of selection, such as nucleotide diversity (Pi) [11], heterozygosity (H p) [12], integrated haplotype score (iHS) [13], Fixation index (F ST) [14], cross-population extended haplotype homozygosity (XP-EHH) [15], and the cross-population composite … days inn jersey city nj