Webb13 apr. 2024 · lactylation. Nature 574, 575-580. 10.1038/s41586-019-1678-1. 8. Chen, Y., Sprung, R ... Here we report the identification and verification of a β-hydroxybutyrate-derived protein modification, ... Webb17 sep. 2024 · Meantime, we found that phosphorylation modification showed no obvious changes during high-altitude adaptation. Furthermore, Figure 11G and H demonstrated that lactylation modification mainly expressed at the protein molecular weight of 25kD. Interestingly, we found that lactylation modification was increased along with high …
Metabolic regulation of gene expression by histone lactylation
Webb26 okt. 2024 · Lysine lactylation (Kla) is a newly discovered histone post-translational modification (PTM), playing important roles in regulating transcription in macrophages. However, the extent of this PTM in non-histone proteins remains unknown. Here, we report the first proteomic survey of this modification in Botrytis cinerea, a destructive … WebbLactylation: a Passing Fad or the Future of Posttranslational Modification Authors Qi Xin # 1 , Hai Wang # 1 , Qinglin Li 1 , Sinan Liu 1 , Kai Qu 2 , Chang Liu 3 4 , Jingyao Zhang 5 6 … barbara kays cooper
Modification of Proteins by Metabolites in Immunity
Webb26 apr. 2024 · L -Lactylation is a recently discovered post-translational modification occurring on histone lysine residues to regulate gene expression. However, the substrate scope of lactylation, especially that in non-histone proteins, remains unknown, largely due to the limitations of current methods for analyzing lactylated proteins. Webb26 apr. 2024 · Furthermore, lactylation modifications have primarily been studied on histones as of late, but we hypothesize that lactylation also occurs on non-histone … Webb13 okt. 2024 · Researchers found social stress specifically enhances lysine lactylation of histone H1 proteins. Source: Fujita Health University. Being bullied leaves a biochemical … barbara kean actress